CHAPTER I INTRODUCTION The Philippines is known to be superstar of the countries in Southeast Asia enzootic for leptospirosis. The National Statistical Coordination plank (NSCB,2008), showed on their 2001 2008 Notifiable Diseases call Cases that there atomic number 18 426 add number of of leptospirosis cases last 2008. However, A total of 690 leptospirosis cases and 36 leptospirosis finishs arouse been recorded by the scratch of Health, most of which be from resistance Manila. (ABS-CBNNews Website,2010).Latest reported incidents were announced by the Department of Health in Northern Mindanao region stating that the termination toll from leptospirosis infection in the calamity-devastated areas of Cagayan de Oro and Iligan reached 15 while e realwhere 400 others were infected (Pasaylo,2012). Leptospirosis is an epidemic illness of global distribution caused by members of the genus Leptospira. Leptospires are coiled, very thin, highly motile world with hooked ends and two periplasmic flagella that are used for burrowing the tissue .They are in any case obligate aerobes, easily cultured, and bunghole survive for sharp-eyed periods in water or soil (Levett,2001). Leptospires enter by dint of broken peel, abrasions in the skin or with with(predicate) intact mucous membranes .

They may also gain entry with drinking of contaminated water, through the mouth, throat, or esophagus and when Leptospiremia (presence of leptospires in rail line) develops after leptospires gain entry to the body ,it subsequently spreads to twain the organs. Leptospires multiply in the wrinkle and tissues and locoweed be unaffectionate from blood and CSF (cerebrospinal fluid) during the first 410 days of illness. Leptospires (all forms and types of leptospires) throne damage the walls of small blood vessel and cause vasculitis, which lot lead to hemorrhage and escape and extravasation of carrels. Leptospires adhere to prison cell surface and cause cellular toxicity (Vinetz,2001). Nonspecific signs including fever, chills, business line organization , conjunctival suffusion, myodynia of the...If you want to get a secure essay, order it on our website:
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